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“I’m feeling mu=
ch
better now, thanks.”
Immunology II
AKAWhy we aren’= t sick ALL of the time
Immune System Basics
•Function
=3D Recognize and Destroy Pathogens
![](3D"slide0002_image001.gif")
![](3D"slide0002_image002.gif")
Disea=
se-causing
organisms
![](3D"slide0002_image003.gif")
Ce=
ll
surface carbohydrates act as “name tags”=
;
![](3D"slide0002_image004.gif")
![](3D"slide0002_image005.gif")
If no=
n-se=
lf/abnormal=3D
ANTIGENS=
ANTIGENS=
![](3D"slide0002_image006.gif")
Infla=
mmatory
response
![](3D"slide0002_image007.gif")
Make ANTIBODIES=3D Special proteins that =
bi=
nd to
specific antigens
![](3D"slide0002_image009.gif")
Make MEMORY
CELLS =3D
“know” how to recognize and destroy =
=3D>Immunity
![](3D"slide0002_image010.gif")
AND
![](3D"slide0003_image012.jpg")
Developing Immunity:
A How-To Guide<= /div>
A How-To Guide<= /div>
-Basicall=
y, you
must make memory cells
![](3D"slide0003_image013.gif")
But, how do I do that?
EXPOSURE TO ANTIGENS
This way, you make antibodies for yourself =3D=
ACTIVE IMMUNITY
You should be asking yourself,
=
; &n=
bsp;
“But, won’t I get sick that way and feel like
doodie?”
Vaccinatio=
ns
AKA Immunizations or Innocul= ations
AKA Immunizations or Innocul= ations
•Present body with antigens but skip th=
e getting
sick part (inflammatory response).
•Use weakened or dead pathogens.
•They still have antigens but cannot
infect
cells.
•Without cellular damage, no inflammato=
ry response
but antibodies and memory cells produced =3D IMMUNITY
Do this by:
<=
span
style=3D'color:#009900'>•Breast fee=
ding
– Mom passes antibodies to baby through breast
milk.
![](3D"slide0005_image014.jpg")
![](3D"slide0005_image015.gif")
If
that’s ACTIVE=
=
immunity, what about
PASSIVE =
immunity?
Speaking of transfusions, what
about:
Tis= sue/Organ Transplanting?
Tis= sue/Organ Transplanting?
•One persons cell surface carbohydrates=
are
another persons antigens
•Matching of “name tags”
critical to transplanting
•Blood-typing is one method of matching =
name
tags
ABO Blood-typing
•Type A blood has
Type AB blood has
Type B blood has
Type O blood has
A antigens
B antigens
Neither A or B
antigens
Both A and B an=
tigens
H=
ere’s
the problem: You always make antibodies against the antigens you DON’T have.
Who can donate=
to
whom?
•Who can donate to anyone?
• Why?
•Who can receive from anyone?
• Why?
' + ENDSHOW_MESG + '
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tes![](3D"buttons.gif")
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